Differential intrinsic functional connectivity changes in semantic variant primary progressive aphasia
نویسندگان
چکیده
منابع مشابه
Impaired Interoceptive Accuracy in Semantic Variant Primary Progressive Aphasia
Background Interoception (the perception of internal bodily sensations) is strongly linked to emotional experience and sensitivity to the emotions of others in healthy subjects. Interoceptive impairment may contribute to the profound socioemotional symptoms that characterize frontotemporal dementia (FTD) syndromes, but remains poorly defined. Methods Patients representing all major FTD syndro...
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OBJECTIVE The semantic variant of primary progressive aphasia (svPPA) is typically associated with frontotemporal lobar degeneration (FTLD) with longTAR DNA-binding protein (TDP)-43-positive neuropil threads and dystrophic neurites (type C), and is only rarely due to a primary tauopathy or Alzheimer's disease. We undertook this study to investigate the localisation and magnitude of the presumed...
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Report of aCase |Theclinical, neuropsychometric, and imaging featuresof this casepreviouslywere reported in2008.2Briefly, awoman in her 60swas referred to the Behavioral Neurology Clinic formemory loss, characterizedbydifficulty rememberingnames.Longitudinal evaluations revealedprogressiveanomia with loss of word knowledge, prosopagnosia, and surface dyslexia. Her last completed neuropsychometr...
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Prototypical items within a semantic category are processed faster than atypical items within the same category. This typicality effect reflects normal representation and processing of semantic categories and when absent may be reflective of lexical-semantic deficits. We examined typicality effects in individuals with semantic and nonsemantic variants of primary progressive aphasia (PPA; semant...
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A 66-year-old woman presented with 4 years of progressive speech difficulty. She had nonfluent speech with phonemic errors but intact single-word comprehension and object knowledge. Her grammar was impaired in both speech and writing, and she exhibited orofacial apraxia. A clinico-radiologic (see figure) diagnosis of nonfluent variant primary progressive aphasia was made. Nonfluent variant prim...
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ژورنال
عنوان ژورنال: NeuroImage: Clinical
سال: 2019
ISSN: 2213-1582
DOI: 10.1016/j.nicl.2019.101797